for Limitations of Use. LEARN ABOUT RYBELSUS®. RYBELSUS® lowered blood sugar better than a leading branded pilla. Adults with an average starting A1C of 8.3% lowered their A1C by an average of: -1.0% on 7 mg of RYBELSUS ®. -1.3% on 14 mg of RYBELSUS ®. -0.8% on 100 mg of JANUVIA ®. SEE STUDY RESULTS.